Definition: Cholera vaccination live oral vaccine is a live attenuated, inactivated cholera vaccine which does not contain any live bacteria or viruses but is designed to protect against cholera, the most common infectious disease caused by Vibrio cholerae bacterium. This type of vaccine is administered orally and can be given as an intramuscular (IM) injection or subcutaneous (SC) injection. The administration route of the live oral vaccine is determined by the manufacturer's instructions. The specific features of this vaccine include: - It does not contain any live bacteria or viruses, so it is 100% effective against cholera. - The vaccine dose is typically given as an IM injection, but some manufacturers may administer it through subcutaneous (SC) injection. - The vaccine must be stored at a temperature of about 4°C to 5°C for optimal storage and reduce the risk of spoilage and degradation. The primary benefit of this vaccine is its low cost, as well as its high level of protection from cholera. It can be administered to individuals who are at high risk of getting cholera, such as those with compromised immune systems or those who have recently traveled abroad. However, it should not be used for routine vaccination in children due to the lack of protection against diarrhea and other complications caused by Vibrio cholerae infection.
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